The Biomolecular Photonics research group of Prof. Dr. Thomas Huser develops novel high-resolution optical microscopy techniques to examine biological and biomedical samples. Both, fluorescence-based and marker-free, chemically sensitive methods (e.g. Raman scattering) are being developed. The research group continuously improves these optical methods and also develops complete system solutions from optomechanics, optoelectronics, laser sources, control based on microcontrollers based on microcontrollers, through to the programming of software for data acquisition and data evaluation. Current third-party funded projects include the development of new methods for high-resolution fluorescence microscopy of living cells to study the membrane dynamics of liver endothelial cells, the development of novel 3D imaging methods with contrast in the short-wave infrared spectral range to support minimally invasive surgery, and the development of fast methods to compensate for motion artifacts using adaptive optics.
The PhD candidate position is part of the EU-funded Marie-Sklodowska-Curie-Action doctoral candidate network "ImAge-D". The advertised position is part of the EU-funded Marie-Sklodowska-Curie-Action doctoral network "ImAge-D". The project at Bielefeld University comprises the development of novel, fast and multicolor super-resolution imaging techniques based on structured illumination microscopy. The applicant is expected to co-develop this system. The candidate will primarily develop software solutions for the control of the microscope, the graphical user interface, the recording and processing of data in real time, the display of data during recording and the evaluation of data sets recorded over a longer period of time. The microscope will then be used for the visualization of nanostructures in optically clarified or living organ cultures. The system will also be used to develop and test new, high-resolution methods of spatial transcriptomics. Research stays (secondments) are planned at the University of Tromsø (Norway, supervisor Sørensen, 2 months), at the Iberian Nanoscience Laboratory (INL, Portugal, supervisor de Beule, 1 month) and at the University of Münster (Germany, supervisor Kiefer, 2 months).
Employment is conducive to scientific qualification.
- salary according to Remuneration level 13 TV-L
- befristet (3 years) (§ 2 (1) sentence 1 of the WissZeitVG; in accordance with the provisions of the WissZeitVG and the Agreement on Satisfactory Conditions of Employment, the length of contract may differ in individual cases)
- internal and external training opportunities
- variety of health, consulting and prevention services
- reconcilability of family and work
- completed scientific studies (e.g. Master or Diploma) in the field of physics or engineering sciences
- experience in the development and operation of super-resolution optical fluorescence microscopes, in particular based on single molecule localization and/or structured illumination
- experience in programming microcontrollers or FPGAs and graphical user interfaces
- experience in the design, control, optimization and operation of optomechanical and electro-optical systems, such as lasers, light-emitting diodes, modulators, micrometer translation stages, scientific cameras, galvanometer mirrors, etc.
- very good knowledge of written and spoken English
- ability to cooperate and to work in a team
- presentation skills
Successful candidate may not have worked and resided in Germany for more than 12 months within the last 3 years (EU requirement for EU-MSCA-DN projects)
- general knowledge in the fields of optics, spectroscopy, lasers and electronics
- experience with programming languages, e. g. MATLAB, LabVIEW, Python or C++
- basic knowledge of programming automated measurement methods and evaluation procedures
- basic knowledge of laser physics
We are looking forward to receiving your application. To apply, please preferably use our online form via the application button below.
application deadline: 21.03.2024