The Faculty of Chemistry, research group Structural Biochemistry, has the following job opening:
- starting: 01.11.2026
- Teilzeit 50 %
- salary according to Remuneration level E13 TV-L
- befristet
The Structural Biochemistry Research Group investigates the structure-function relationship of proteins. A key area of focus is bacterial virulence factors, including the type III secretion system (T3SS) of the human-pathogenic bacterium Yersinia enterocolitica (e.g. Gilzer et al., Nat Commun. 2022, doi 10.1038/s41467-022-30487-1). To continue an ongoing project, we are seeking a candidate who, with enthusiasm, commitment and attention to detail, wishes to investigate the molecular function of individual T3SS proteins and their interactions, using biochemical and X-ray crystallography methods. There is an opportunity to pursue a PhD within the research group’s project.
- contributing to research projects on the structure and molecular function of proteins (60 %)
- molecular biology work (cloning, mutagenesis, etc.)
- recombinant protein expression, primarily in E. coli
- functional analyses (e. g. binding assays, enzyme assays, spectroscopy, etc.)
- protein purification and protein crystallisation
- X-ray diffraction experiments, data analysis, structure determination
- Documentation and publication
- teaching duties involving the supervision of practical sessions and tutorials in biochemistry and Chemistry, 2 LVS (25 %)
- organisational duties within the research group (15 %)
Employment is conducive to scientific qualification and provides the opportunity for further academic development.
- salary according to Remuneration level E13 TV-L
- befristet (3 Years) (§ 2 (1) sentence 1 of the WissZeitVG; in accordance with the provisions of the WissZeitVG and the Agreement on Satisfactory Conditions of Employment, the length of contract may differ in individual cases)
- Teilzeit 50 %
- internal and external training opportunities
- variety of health, consulting and prevention services
- reconcilability of family and work
- collegial working environment
- open and pleasant working atmosphere
- exciting, varied tasks
- various offers (canteen, cafeteria, restaurants, Uni-Shop, ATM, etc.)
- completed university degree (M.Sc. or equivalent) in biochemistry or a related scientific discipline
- in-depth knowledge of biochemistry, Molecular Biology and biophysical Chemistry
- practical experience with molecular biology techniques and recombinant protein expression
- practical experience with protein purification
- ability to work independently, meticulously and with dedication
- ability to work as part of a team
- very good command of spoken and written English and a good command of spoken and written German
- desire to pursue a doctorate
- knowledge of protein structure determination
- practical experience of protein crystallisation and X-ray structural analysis
- practical experience of biophysical methods (e. g. DSF, MST, BLI, ITC, CD, SPR, etc.)
- practical experience in investigating protein-protein interactions
We are looking forward to receiving your application. To apply, please preferably use our online form via the application button below.
Prof. Dr. Hartmut Niemann
+49521-106 6154
hartmut.niemann@uni-bielefeld.de
Postal Address
Universität Bielefeld
Biochemie IV
Prof. Dr. Hartmut Niemann
Postfach 10 01 31
33501 Bielefeld
